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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5B
All Species:
23.64
Human Site:
S196
Identified Species:
40
UniProt:
P61020
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61020
NP_002859.1
215
23707
S196
L
G
G
A
A
G
R
S
R
G
V
D
L
H
E
Chimpanzee
Pan troglodytes
XP_001153865
294
32235
S275
L
G
G
A
A
G
R
S
R
G
V
D
L
H
E
Rhesus Macaque
Macaca mulatta
XP_001096821
335
36686
S316
L
G
G
T
A
C
R
S
R
G
V
D
L
H
E
Dog
Lupus familis
XP_856128
222
24457
S203
L
G
G
A
A
G
R
S
R
G
V
D
L
H
E
Cat
Felis silvestris
Mouse
Mus musculus
P35278
216
23394
T197
A
A
G
A
P
G
R
T
R
G
V
D
L
Q
E
Rat
Rattus norvegicus
Q6GQP4
194
21350
N176
L
D
P
H
E
N
G
N
S
G
G
I
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
G196
P
G
A
N
S
A
R
G
R
G
V
D
L
T
E
Chicken
Gallus gallus
Q5ZHW4
215
23596
S196
T
S
G
A
A
G
R
S
R
G
V
D
L
H
E
Frog
Xenopus laevis
NP_001080714
215
23616
N197
A
Q
S
T
T
G
R
N
R
G
V
D
L
Q
E
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
S197
A
G
A
N
S
G
R
S
R
G
V
D
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
N197
T
S
G
Q
R
G
T
N
R
G
V
D
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
A185
A
A
A
N
A
R
P
A
T
V
Q
I
R
G
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
G182
Q
P
A
E
N
P
T
G
M
V
L
P
N
G
P
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
R192
E
R
E
S
N
N
Q
R
V
D
L
N
A
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.1
60.9
96.8
N.A.
84.2
45.1
N.A.
81.8
96.2
83.2
81
N.A.
N.A.
N.A.
N.A.
83.3
Protein Similarity:
100
73.1
60.9
96.8
N.A.
91.1
63.7
N.A.
91.1
97.6
91.1
90.7
N.A.
N.A.
N.A.
N.A.
89.3
P-Site Identity:
100
100
86.6
100
N.A.
66.6
13.3
N.A.
53.3
86.6
53.3
66.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
86.6
100
N.A.
73.3
20
N.A.
60
86.6
60
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
40.9
N.A.
58.1
53.9
N.A.
Protein Similarity:
N.A.
56.7
N.A.
70.2
66.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
15
29
36
43
8
0
8
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
72
0
0
0
% D
% Glu:
8
0
8
8
8
0
0
0
0
0
0
0
0
0
72
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
43
50
0
0
58
8
15
0
79
8
0
0
15
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
36
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
36
0
0
0
0
0
0
0
0
0
15
0
72
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
22
15
15
0
22
0
0
0
8
8
0
8
% N
% Pro:
8
8
8
0
8
8
8
0
0
0
0
8
0
0
8
% P
% Gln:
8
8
0
8
0
0
8
0
0
0
8
0
0
15
8
% Q
% Arg:
0
8
0
0
8
8
65
8
72
0
0
0
8
0
0
% R
% Ser:
0
15
8
8
15
0
0
43
8
0
0
0
0
0
0
% S
% Thr:
15
0
0
15
8
0
15
8
8
0
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
0
8
15
72
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _